Hepcinat (Sofosbuvir) and Hepcinat-LP (Ledipasvir/Sofosbuvir) are the breakthrough treatments for Hepatitis C infections. Its mechanism of action involves inhibiting the enzyme which is necessary for the virus if it is to multiply.
Hepcinat (Sofosbuvir) and Hepcinat-LP (Ledipasvir/Sofosbuvir) are the breakthrough treatments for Hepatitis C infections. Its mechanism of action involves inhibiting the enzyme which is necessary for the virus if it is to multiply. A complete cure may even be possible. Chronic hepatitis C is a serious infection of the liver which occurs following an infection with the hepatitis C virus. Upon reaching the cells of the liver, the virus begins to multiply, which it achieves by means of copying its DNA and RNA. This medicine is known as a nucleotide polymerase inhibitor, and it works directly on the virus itself.
After oral administration, it undergoes a process of intracellular metabolism in which it is converted to its active form. It subsequently starts to work, whereupon it actively targets the enzyme that is used by the virus to produce RNA chains (HCV NS5B RNA-dependent RNA polymerase). This can help to stop viral multiplication. Treatment of genotypes 1, 2, 3 and 4 is possible with this medicine, however it is always used in combination with other medications and never on its own.
Dosage and Administration for Hepcinat
Hepcinat (Sofosbuvir) or Hepcinat-LP (Ledipasvir/Sofosbuvir) film coated tablets each contain 400mg of the main ingredient. The dosage schedule must be individualized by the physician in charge of treatment, and will vary according to the viral genotype that is being treated. Adult patients will usually be directed by their physician to take 1 tablet per day, and it can be administered alongside a meal or else without food.
Those suffering from GT1 or GT4 (genotype 1 or 4) may be ordered by the physician to take it alongside ribavirin and peginterferon alfa, with treatment lasting for a period of 12 weeks. In contrast to this, GT2 (genotype 2) is usually treated for 12 weeks, and it is taken alongside ribavirin. GT3 (genotype 3) requires 24 weeks of treatment in combination with ribavirin. Patients must only take it according to the instructions provided to them by the physician in charge of treatment.
Mechanism of Action of Hepcinat:-
Sofosbuvir contains oral nucleotide analog inhibitor of the hepatitis C virus (HCV) polymerase. The drug is a direct-acting antiviral agent and interferes straight with the HCV lifecycle, restraining the viral replication. It can be incorporated into HCV RNA by the NS5B polymerase and acts as a chain terminator. The drug is available for oral use in the form of 400mg tablets.
- Composition: – Each film coated tablet contains: Sofosbuvir equivalent to Sofosbuvir 400mg
- Packaging: – Each Bottle contains 28 tablets of Sofosbuvir 400mg.
- Storage: – Store at 25°C in a dry place.
Adverse effects of Hepcinat:-
Patients using Hepcinat may encounter unwanted side effects such as:
- Loss of appetite
- Lower back or side pain
Contact a doctor immediately should side effects persist or if you encounter more severe side effects such as:
- Pale skin
- Mental or mood changes
- Excessive fatigue
- Signs of new infection
- Changes in behavior
- Irregular heartbeat
- Trouble breathing
A new pill HEPCINAT seen as a genuine breakthrough in the treatment of chronic hepatitis C has recently emerged in the world pharmaceutical market. Not only does it have a very high efficacy, but it is also very well tolerated. As part of a standard combination therapy, Sofosbuvir can now replace Interferon which is commonly known for causing certain adverse effects and having a number of contraindications. At the moment, it is already approved for use in the 120 countries worlwide. SOFOSBUVIR can be used for treatment of patients with cirrhosis and HIV.
|Indian Brand Name:||HEPCINAT|
|Manufacturer:||Natco Pharma Ltd.|
|Packaging:||Bottle of 28 Tablets|
|Availability / Pricing:||Ready for Dispatch|
|Delivery Time:||7 — 14 Days|
It seen as a genuine breakthrough in the treatment of chronic hepatitis C has recently emerged in the world pharmaceutical market. Not only does it have a very high efficacy, but it is also very well tolerated. As part of a standard combination therapy, Sofosbuvir can now replace Interferon which is commonly known for causing certain adverse effects and having a number of contraindications..
TRADE NAME HEPCINAT IS GENERIC VERSION OF SOFOSBUVIR.
Manufactured by Natco Pharma Ltd. (INDIA)
Missing a dose
Overdosage of Hepcinat Tablet
- Never take more medicine than the prescribed dose. Eating more medicine will not improve your symptoms, rather they may cause poisoning or serious side effects. If you suspect that you or anyone else may have taken an overdose of Hepcinat Tablet, please go to the emergency department of the closest hospital or nursing home. Carry the medicine box, container or label with you to help doctors with necessary information.
- Never give your medicines to other people even if you know that they have the same condition or it seems that they have similar conditions. This maylead to overdosage or medicine poisoning.
- Please consult your physician or pharmacist or product package for more information.
Storage of Hepcinat Tablet
- Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless the packaging or storage instructions clearly require you to do that. Keep medicines away from children and pets to prevent them from accidental consumption.
- Do not flush medicines down the toilet or pour them into drainage unless specifically instructed to do so. Medicines discarded in this manner will enter the natural environment or be consumed by wildlife. This can cause irreparable environmental damage. Please consult your pharmacist or doctor for more details on how to safely discard Hepcinat Tablet.
Expired Hepcinat Tablet
- Consuming a single dose of expired Hepcinat Tablet is unlikely to be harmful enough to produce an adverse event. However, please discuss with your primary health provider or your pharmacist for proper advice or if you feel unwell, sick or uneasy. Expired medicine could have become less effective over the years and might not be efficacious enough to treat the disorder for which it was prescribed. To be on the safe side, it is more prudent not to make a habit of taking expired medication. It is better to stick to unexpired ones. If you have a chronic illness that requires taking medicine constantly such as heart condition, seizures, and life-threatening allergies, you are much safer keeping in touch with your primary health care provider so that you can have a fresh supply of unexpired medications.