What is Iressa?
Iressa (gefitinib) is a cancer medication that interferes with the growth and spread of cancer cells in the body.
Iressa is used to treat non-small cell lung cancer.
Iressa is sometimes used to treat cancer that has spread to other parts of the body.
How should I use Iressa?
Iressa should only be administered under the supervision of a qualified healthcare provider experienced in the use of cancer chemotherapeutic agent.
Your doctor will perform blood tests to make sure you have the correct tumor type to be treated with Iressa.
Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.
You may take Iressa with or without food.
How to use gefitinib
Take gefitinib by mouth once daily, with or without food, or as directed.
Medications which reduce or completely block stomach acid (e.g., proton pump inhibitors/PPIs, H2 blockers, antacids) may decrease the absorption of gefitinib. This could decrease the effectiveness of gefitinib. Consult your doctor or pharmacist if you are taking any of these medications.
Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same time each day…
Treatment by Condition Related to gefitinib
- Non-Small Cell Lung Cancer Medications
- Epidermal Growth Factor Receptor Positive Non-Small Cell Lung Cancer Medications
Gefitinib is a kinase inhibitor.
The chemical name of gefitinib is 4-Quinazolinamine N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl) propoxy] and the following structural formula:
Gefitinib has the molecular formula C22H24ClFN4O3, a relative molecular mass of 446.9 daltons and is a white-colored powder. Gefitinib is a free base. The molecule has pKas of 5.4 and 7.2. Gefitinib can be defined as sparingly soluble at pH 1, but is practically insoluble above pH 7, with the solubility decreasing sharply between pH 4 and pH 6. In non-aqueous solvents, gefitinib is freely soluble in glacial acetic acid and dimethyl sulfoxide, soluble in pyridine, sparingly soluble in tetrahydrofuran, and slightly soluble in methanol, ethanol (99.5%), ethyl acetate, propan-2-ol and acetonitrile.