Entecavir is used for:
Treating HBV infection in certain patients.
Entecavir is a nucleoside analogue. It works by reducing the amount of HBV in the blood. It also helps prevent the HBV from multiplying and infecting new liver cells.
Do NOT use entecavir if:
you are allergic to any ingredient in entecavir
you have HIV infection and you are not receiving HAART
Contact your doctor or health care provider right away if any of these apply to you.
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Before using entecavir:
Some medical conditions may interact with entecavir. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have HIV infection or kidney problems, or if you are on dialysis
if you have a history of liver problems or you have had a liver transplant
if you are very overweight
if you have received medicine to treat hepatitis B in the past, or if you have been taking nucleoside analogues for a long time
Some MEDICINES MAY INTERACT with entecavir. Tell your health care provider if you are taking any other medicines, especially any of the following:
Medicines that may harm the kidney (eg, aminoglycoside antibiotics [eg, gentamicin], amphotericin B, cyclosporine, nonsteroidal anti-inflammatory drugs [NSAIDs] [eg, ibuprofen], tacrolimus, vancomycin) because they may increase the risk of entecavir’s side effects. Ask your doctor if you are unsure if any of your medicines may harm the kidneys.
This may not be a complete list of all interactions that may occur. Ask your health care provider if entecavir may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use entecavir:
Use entecavir as directed by your doctor. Check the label on the medicine for exact dosing instructions.
An extra patient leaflet is available with entecavir. Talk to your pharmacist if you have questions about this information.
Take entecavir on an empty stomach, at least 2 hours after a meal and at least 2 hours before the next meal.
Entecavir works best if it is taken at the same time each day.
Continue to take entecavir even if you feel well. Do not miss any doses.
If you miss a dose of entecavir, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use entecavir.
Important safety information:
- Entecavir may cause dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use entecavir with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Entecavir does not stop you from spreading HBV to others through sexual contact, sharing needles, or being exposed to your blood. Use barrier methods of birth control (eg, condoms) if you have HBV infection. Talk with your doctor about safe sexual practices that protect your partner. Never share needles or other injection supplies. Do not share personal items that may have blood or body fluids on them, like toothbrushes or razors. A vaccine is available to protect people at risk from becoming infected with HBV.
- Do not change your dose without checking with your doctor.
- Entecavir is not a cure for HBV infection. Remain under the care of your doctor.
- When your medicine supply is low, get more from your doctor or pharmacist as soon as you can. Do not stop taking entecavir, even for a short period of time. If you do, the virus may grow resistant to the medicine and become harder to treat.
- LAB TESTS, including liver and kidney function and HIV and HBV antibody, may be performed while you use entecavir and for several months after you stop entecavir. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use entecavir with caution in the ELDERLY; they may be more sensitive to its effects.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking entecavir while you are pregnant. It is not known if this medicine is found in breast milk. Do not breast-feed while taking entecavir.